Alchemy / manufacture perks
Upon reaching 100% alchemy and / or manufacture, you gain bonus perks
Alchemy:
25% more healing with pots
25% more mana with pots
25% longer effects of potions
Manufacture:
25% chance of not losing durability when using weapon/wand or from armor after being hit.
*another idea would be 25% more durability of any weapon/armor equiped (not sure if that's possible)